Recent Advances in RNA Interference Therapeutics for CNS Diseases
نویسندگان
چکیده
منابع مشابه
RNA Therapeutics for Treatment of Cardiovascular Diseases
Recent studies suggest that the majority of the human genome is transcribed, but only ≈2% account for protein coding exons. The remaining noncoding sequences include small noncoding RNAs, particularly microRNAs, which are ≈22 nucleotides in length. MicroRNAs posttranscriptionally control gene expression by targeting multiple mRNAs. By binding to the 3′UTR (untranslated region) of mRNAs, microRN...
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ژورنال
عنوان ژورنال: Neurotherapeutics
سال: 2013
ISSN: 1933-7213,1878-7479
DOI: 10.1007/s13311-013-0183-8